Luminos: Life, interactive

Our Products

Upright ultra wide-field microscope system

Luminos' upright microscope is optimized for imaging complex tissues and in vivo. The top-down view can image acute brain slices, zebrafish embryos, and rodent brain activity in head-fixed behaving animals. The system includes integration with virtual reality and other behavioral protocols.

Technical specifications

Inverted ultra wide-field microscope system

Luminos' inverted microscope is optimized for imaging cell cultures. The automated stage accommodates multi-well plates or single-well dishes. The system has full environmental control, autofocus, and capability for long-term or iterated acquisitions.

Technical specifications

Instrument control software

The Luminos instrument control software provides seamless integration of imaging, patterned illumination, and all other experimental parameters.

The Luminos software is freely available for non-commercial use.
Subscriptions are available for technical support.
Licensing options are available for commercial use.

Light-responsive biological materials

Luminos can provide:

Transgenic mice, genetically engineered to express either a voltage indicator or a combination of voltage indicator and spectrally orthogonal optogenetic actuator. All mice are available with either Cre dependence, Flp dependence, or intersectional Cre- and Flp dependence.
Human induced pluripotent stem cell (hiPSC) lines genetically engineered to co-express a channelrhodopsin and a voltage indicator.
Optopatch HEK cell lines genetically engineered to express a channelrhodopsin, a voltage indicator, and various ion channels.
AAV vectors for rodent expression of Optopatch and other light-responsive actuators and reporters.

Light-responsive chemicals

Luminos can provide:

Photochemical tools for light-directed click chemistry, with either violet or near-IR activation;
Photochemical crosslinkers to control cell adhesion to a dish.